Protocol Components
Duration & Cycling: Continuous (with Epithalon cycled)
Morning
Inject BPC-157 (250mcg) Daily
Systemic repair base.
Pre-Workout/AM
Inject MOTS-c (5mg) 3x/Week
Metabolic activation.
Night
Inject Thymosin Alpha-1 (1.6mg) 2x/Week
Immune modulation.
Cycle (2x/Year)
Epithalon (5-10mg) Daily for 10-20 days
Telomere reset cycle.
Mechanism of Action
This stack represents a comprehensive 'biological insurance policy' by targeting the four pillars of aging: Mitochondrial Decline (MOTS-c), Telomere Shortening (Epithalon), Systemic Inflammation/Repair (BPC-157), and Immune Senescence (Thymosin Alpha-1).
1. MOTS-c (Energy): Targets metabolic health by mimicking exercise, improving insulin sensitivity, and preventing age-related weight gain.
2. Epithalon (Time): Acts as a telomerase activator to maintain DNA integrity and reset circadian rhythms via the pineal gland.
3. BPC-157 (Repair): Provides ongoing cytoprotection for the gut and connective tissues, managing the daily 'wear and tear' of life.
4. Thymosin Alpha-1 (Defense): Calibrates the immune system, preventing both immunodeficiency (infection) and autoimmunity (chronic inflammation).
Synergy: Together, they create a homeostatic loop where energy production, DNA repair, tissue maintenance, and immune surveillance operate at youthful levels simultaneously.
References
- MOTS-c2025MOTS-c improves mitochondrial bioenergeticsFrontiers in PhysiologyStudy on restoration of ATP production in diabetic tissues.
- MOTS-c2024MOTS-c prevents muscle atrophyiScienceHighlights glucose uptake via GLUT4 and mitochondrial fusion.
- Epithalon (Epitalon)2003 (Pivotal)Epithalon elongates telomeresBull Exp Biol MedDemonstrated telomerase activation in somatic cells.
- Epithalon (Epitalon)2004Normalization of pineal functionNeuro Endocrinol LettRestoration of melatonin rhythms in elderly subjects.
- BPC-1572025Emerging Use of BPC-157 in Orthopaedic Sports MedicinePubMed CentralSystematic/narrative review summarizing preclinical musculoskeletal findings and discussing limited human evidence.
- BPC-1572025Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal HealingPubMed CentralNarrative/scoping review focusing on mechanisms, potential applications, and safety concerns in musculoskeletal contexts.
- BPC-1572025Stable Gastric Pentadecapeptide BPC 157 as Therapy After Quadriceps Muscle-to-Bone Detachment to Reattachment in RatsPubMedPreclinical rat study exploring functional recovery after muscle-to-bone injury with BPC-157 therapy.
- Thymosin Alpha-12021Thymosin alpha 1 mitigates cytokine stormOpen Forum Infect DisClinical data on reducing mortality in severe viral infections.
- Thymosin Alpha-12025Immunomodulation in sepsisFrontiers in ImmunologyRestoration of CD4+/CD8+ ratios and reduced CRP.
Used For
Total Body Rejuvenation
Enhanced Immune Defense
Metabolic Flexibility
DNA Repair
Important Notes
Injection Fatigue
High injection volume/frequency. Rotate sites frequently.
Research Use OnlyThis information is for educational and research purposes only. Always consult properly licensed professionals.