Protocol Components
Duration & Cycling: 8 to 12 Weeks
Daily (AM)
Inject SS-31 (4mg)
Take for first 30 days to prime the system.
3x/Week
Inject MOTS-c (5mg)
Add in after first week of SS-31.
Mechanism of Action
This protocol is often called the 'Hardware & Software' upgrade for cellular energy.
1. SS-31 (The Mechanic): A targeted antioxidant that concentrates in the inner mitochondrial membrane (cristae). It physically repairs the 'machinery' of the electron transport chain, restoring efficiency in old or damaged mitochondria.
2. MOTS-c (The Signal): A mitochondrial signal that promotes 'biogenesis' (the creation of NEW mitochondria).
Synergy: If you only take MOTS-c, you might just be whipping a tired horse. By adding SS-31, you first heal the horse (restore efficiency), then ask it to run (biogenesis). This is the gold standard for treating Chronic Fatigue and age-related energy decline.
References
- MOTS-c2025MOTS-c improves mitochondrial bioenergeticsFrontiers in PhysiologyStudy on restoration of ATP production in diabetic tissues.
- MOTS-c2024MOTS-c prevents muscle atrophyiScienceHighlights glucose uptake via GLUT4 and mitochondrial fusion.
Used For
Restored Cellular Energy
Reduced Oxidative Stress
Improved Endurance
Cognitive Clarity
Important Notes
Mild Stimulation
Can feel like too much coffee; adjust MOTS-c dose if jittery.
Research Use OnlyThis information is for educational and research purposes only. Always consult properly licensed professionals.