Back to Library
Muscle GrowthHormone Optimization

CJC-1295 (No DAC) + Ipamorelin

Synergistic blend for amplified, natural GH pulses

Overview

This blend combines 5mg of CJC-1295 (No DAC) and 5mg of Ipamorelin. It is widely considered the 'gold standard' for anti-aging and growth hormone optimization because it targets two distinct receptors simultaneously. This synergy creates a massive release of Growth Hormone that is far greater than using either peptide alone, without the side effects (hunger, cortisol) of older generation peptides.

Chemical Information

IUPAC Name
Tetrasubstituted GRF (1-29) + AIB-His-D-2-Nal-D-Phe-Lys-NH2
Sequence
Blend of 2 Peptides
Molecular Mass
Blend (3367.2 Da + 711.9 Da)
Formula
Mixture
Chemical Structure not available

Mechanism of Action

Functions as a Dual-Pathway GH Amplifier. 1. The Initiator (CJC-1295 No DAC): Binds to the GHRH receptor in the pituitary to *initiate* the release of Growth Hormone. 2. The Amplifier (Ipamorelin): Binds to the Ghrelin receptor to *amplify* the strength of that release. Synergy: When used together, they create a 'multiplying effect' (1+1=5) on GH secretion. Crucially, Ipamorelin is selective, meaning it triggers GH without triggering the release of stress hormones (cortisol) or hunger hormones (ghrelin side effects), making it the cleanest way to boost natural GH levels.

Potential Research Fields

SarcopeniaMetabolic SyndromeAnti-AgingPost-Surgery RecoverySleep Quality

Recent Research

This blend represents the modern standard for Hormone Replacement Therapy (HRT) research. Unlike administering synthetic HGH directly (which shuts down the body's own production), the CJC/Ipamorelin blend stimulates the pituitary gland to produce its own hormone. 2024 reviews confirm this maintains the body's natural pulsatile rhythm, preventing the 'GH gut' and insulin resistance associated with synthetic HGH abuse. It is specifically researched for its ability to improve deep wave sleep (SWS) and increase fat oxidation (lipolysis) while the subject sleeps.

Bibliography / Scientific References

Related Peptides

Research
CJC-1295 No DAC

Short-acting GHRH analogue for pulsatile GH research

Research
Follistatin (FST)

Potent myostatin inhibitor for muscle hypertrophy

Peptide Information Guide
Administration Type
Injectable (Subcutaneous)

Injectable administration protocol for research.

Vial Strength
10mg
Reconstitution
Reconstitute with 2ml bacteriostatic water
Dosage Options
0.5 mg (10 units)
Daily (Mon-Fri)
Protocol for 10mg vial/2ml water. (Conc: 5mg/ml. 10 units = 0.1ml = 0.5mg total blend). Take on empty stomach.
Schedule
5 days/week (Before bed)
Timing: One specific day.
Duration
3 Months
Potential Side Effects
Flushing (warmth)
lowcommon (lasts 10-20 mins)
Injection site sensitivity
lowcommon
Research Use Only

This information is for research purposes only. Always consult with a healthcare professional before starting any peptide protocol. Individual responses may vary, and proper medical supervision is recommended for all peptide therapies.